これまでの業績


原著・総説・著書

1. Naitou K, Nakamori H, Shiina T, Ikeda A, Nozune Y, Sano Y, Yokoyama T, Yamamoto Y, Yamada A, Akimoto N, Furue H and Shimizu Y. Stimulation of dopamine D2-like receptors in the lumbosacral defecation centre causes propulsive colorectal contractions in rats. Journal of Physiology (London) in press, 2016

2. Tonomura S, Ebara S, Bgdasarian K, Uta D, Ahissar E, Meir I, Lampl I, Kuroda D, Guruta T, Furue H and Kumamoto K. Structure-function correlations of rat trigeminal primary neurons: Emphasis on club-like endings, a vibrissal mechanoreceptor. Proceedings of the Japan Academy, Series B 91: 560-576, 2015

3. 山田彬博、古江秀昌. 神経障害性疼痛で生じるCl-イオン濃度勾配はGABAで痛みが生じるほど大きな変化でしょうか? LiSA 22: 130-132, 2015

4. Takayama Y, Uta D, Furue H and Tominaga M. Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons. Proceedings of the National Academy of Sciences of the United States of America 112(16): 5213-5218, 2015

5. Nishida K, Matsumura S, Taniguchi W, Uta D, Furue H and Ito S. Three-dimensional distribution of sensory stimulation-evoked neuronal activity of spinal dorsal horn neurons analyzed by in vivo calcium imaging. PLoS One 9(8): e103321, 2014

6. Hickey L, Li Y, Fyson S, Watson T, Perrins R, Hewinson J, Teschemacher A, Furue H, Lumb B, Pickering AE. Opto-activation of locus coeruleus neurons evokes bidirectional changes in thermal nociception in rats. Journal of Neuroscience 34(12): 4148-4160, 2014

7. Funai Y, Pickering AE, Uta D, Nishikawa K, Mori T, Asada A, Imoto K and Furue H. Systemic dexmedetomidine augments inhibitory synaptic transmission in the superficial dorsal horn through activation of descending noradrenergic control: an in vivo patch-clamp analysis of analgesic mechanisms. Pain 155(3): 617-628, 2014

8. 古江秀昌. 下行性制御機構:セロトニン系、ノルアドレナリン系. 日本医師会雑誌 143特別号(1): 42-43, 2014

9. 古江秀昌、歌 大介、秋元 望. 脊髄における侵害受容機構. ファインケミカル 43(1): 17-21, 2014

10. Funai Y, Nishikawa K, Mori T, Asada A, Imoto K and Furue H. Systemic alpha-2 agonist administration facilitates inhibitory synaptic transmission in the rat spinal dorsal horn mediated through alpha-1 adorenoceptors. Pain Research 28(3): 145-153, 2013

11. Hakozaki A, Imoto K, Hayashi Y, Kawatani M and Furue H. In vivo patch-clamp analysis of visceral spinal sensory synaptic transmission and spinal control of lower urinary tract function. Pain Research 28(3): 155-165, 2013

12. 古江秀昌. 中枢性の痛覚抑制機構. Pain Clinic 34(8): 1091-1099, 2013

13. 古江秀昌、井本敬二、杉山大介、川真田樹人、舟井優介、西川精宣. 下行性ノルアドレナリン痛覚抑制機構とその活動制御. 麻酔 61(増刊): S30-40, 2012

14. Xie DJ, Uta D, Feng PY, Wakita M, Shin MC, Furue H and Yoshimura M. Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitro. Molecular Pain 8(1): 58, 2012free article

15. Sugiyama D, Hur SW, Pickering AE, Kase D, Kim SJ, Kawamata M, Imoto K and Furue H. In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem. Journal of Phsyiology (London) 590(10): 2225-2231, 2012

16.Furue H and Kato G. Noradrenaline. Bone Joint Nerve 2(2): 231-237, 2012

17. Furue H. In vivo patch-calmp recording technique. In: Patch Clamp Techniques: From Beginning to Advanced Protocols. (Springer Protocols Handbooks), Springer-Verlag, pp.171-182, 2012

18. Uta D, Furue H, Mizuguchi-Takase H, Imoto K and Yoshimura M. Morphological analyzes of excitatory effect of TRPA1 agonists on synaptic transmission in spinal dorsal neurons. The Journal of Functional Diagnosis of the Spinal Cord 34: 58-64, 2012

19. Lu J, Katano T, Uta D, Furue H and Ito S. Rapid S-nitrosylation of actin by NO-generating donors and inflammatory pain model mice. Molecular Pain 7(1):101, 2011free article

20. Sugiyama D, Imoto K, Kawamata M and Furue H. In vivo patch-clamp analysis of descending noradrenergic control of spinal nociceptive transmission. Pain Research 26(1):1-9, 2011

21. 古江秀昌.In vivo ブラインドパッチ法.In:最新パッチクランプ実験技術法 吉岡書店(岡田泰伸編) pp.115-120, 2011

22. 柳澤義和、歌 大介、川股知之、古江秀昌、岩本幸英、井本敬二、吉村 恵.悪性骨腫瘍性疼痛マウスにおける脊髄興奮性入力の可塑的変化. 脊髄機能診断学 33(1): 8-17, 2011

23. Yanagisawa Y, Furue H, Kawamata T, Uta D, Yamamoto J, Furuse S, Katafuchi T, Imoto K, Iwamoto Y and Yoshimura M. Bone cancer induces a unique central sensitization through synaptic changes in a wide area of the spinal cord. Molecular Pain 6:38, 2010free article

24. Hachisuka J, Furue H, Furue M and Yoshimura M. Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. Journal of Neurophysiology 104(1):271-279, 2010

25. Uta D, Furue H, Pickering AE, Rashid MH, Mizuguchi-Takase H, Katafuchi T, Imoto K and Yoshimura M. TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord. European Journal of Neuroscience 31(11):1960-1973, 2010

26. 古江秀昌、歌 大介.局所麻酔薬光学異性体の痛覚伝達選択的な遮断効果ー基礎生理学的な検討ー. 日本臨床麻酔学会誌 30(4): 535-544, 2010

27. 古江秀昌、杉山大介.生理学の立場から 光学異性体の末梢神経(後根神経節細胞)への作用の違い.レボブピパカインの基礎と臨床.浅田章、西川精宣編, 克誠堂出版, 東京, 51-64, 2010

28. Georgiev SK, Furue H, Baba H and Kohno T. Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons. Molecular Pain 6:25, 2010free article

29. Yanagisawa Y, Furue H, Kawamata T, Uta D, Iwamoto Y, Imoto K and Yoshimura M. Changes in nociceptive behaviors and spinal excitatory synaptic transmission in a murine model of cancer-induced bone pain. The Journal of Functional Diagnosis of the Spinal Cord 32(1): 61-68, 2010

30. Gerogiev S, Furue H, Kohno T. Actions of xenon on the excitatory and inhibitory synaptic transmission in superficial dorsal horn neurons. The Journal of Functional Diagnosis of the Spinal Cord 32(1): 46-52, 2010

31. Uta D, Furue H, Imoto K and Yoshimura M. Actions of local anesthetics on excitatory synaptic transmission to adult rat spinal dorsal horn. The Journal of Functional Diagnosis of the Spinal Cord 32(1): 53-60, 2010

32. Takazawa T, Furue H, Nishikawa K, Uta D, Takeshima K, Goto F and Yoshimura M. Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed by in vitro and in vivo patch-clamp recordings. European Journal of Neuroscience 29(3):518-529, 2009

33. Abe K, Kato G, Katafuchi T, Tamae A,Furue H and Yoshimura M. Responses to 5-HT in morphologically identified neurons in the rat substantia gelatinosa in vitro. Neuroscience 159(1):316-324, 2009

34. Furue H*, Katano T*, Okuda-Ashitaka E, Tagaya M, Watanabe M, Yoshimura M and Ito S (*contributed equally). N-Ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal sord through GluR2 subunit composition switch after inflammation. European Journal of Neuroscience 27(12):3161-3170, 2008

35. Uta D, Furue H, Yoshimura M. Spinal modulation of nociceptive synaptic transmission bia activation of TRPA1 and TRPV1. Pain Research 23(3):141-150, 2008

36. 岡井 恒、古江秀昌、吉村 恵.ノイロトロピンによるセロトニン下行性疼痛抑制系の賦活化と鎮痛作用.Pain Research 23(1):11-18, 2008

37. Yanagisawa Y, Furue H, Kawamata T, Uta D, Namiki A, Iwamoto Y and Yoshimura M. The behavioral and electrophysiological analysis of spinal nociceptive transmission in a murine model of bone cancer pain. The Journal of Functional Diagnosis of the Spinal Cord 30(1):58-62, 2008

38. Uta D, Furue H and Yoshimura M. Comparison of the action potential blocking effects of the local anesthetics in adult rat dorsal root ganglion neurons. The Journal of Functional Diagnosis of the Spinal Cord 30(1):49-57, 2008

39. Furue H* , Suzuki SC*, Koga K, Jiang N, Nohmi, M, Shimazaki Y, Katoh-Fukui Y, Yokoyama M, Yoshimura M, Takeichi M (*contributed equally). Cadherin-8 is Required for the First Relay Synapses to Receive Functional Inputs from Primary Sensory Afferents for Cold Sensation. Journal of Neuroscience 24:3466-3476, 2007

40. Furue H, Katafuchi T, Yoshimura M. In vivo patch. In:Patch-Clamp Analysis: Advanced Technique, Second Edition (Eds. Wolfgang Walz) The Humana Press Inc pp.229-251, 2007

41. Takeshima K, Furue H and Yoshimura M. The role of GABAB receptor in spinal nociceptive transmission. Pain Research 22:33-41, 2007(Review article)

42. Yasaka T, Kato G, Furue H, Rashid MH, Sonohata M, Tamae A, Murata Y, Masuko S and Yoshimura M. Cell type specific excitatory and inhibitory circuits involving primary afferents in the substantia gelatinosa of rhe rat spinal dorsal horn in vitro. Journal of Physiology(London) 581(2):603-618, 2007

43.Furue H and Yoshimura M.Electrophysiological analysis of plastic changes in nociceptive transmission. Pain Clinic 28(1):93-105, 2007(Review article)

44. Rashid MH, Furue H,Yoshimura M and Ueda H. Tonic inhibitory role of alpha4beta2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice. Pain 125(1-2):125-135, 2006

45. Kawamata M, Furue H,Kozuka Y, Narimatsu E, Yoshimura M and Namiki A. Changes in properties of substantia gelatinosa neurons after surgical incision in the rat: In vivo patch-clamp analysis. Anesthesiology 104:432-440, 2006

46. Yoshimura M and Furue H.Mechanisms for the Anti-nociceptve Actions of the Descending Noradrenergic and Serotonergic Systems in the Spinal Cord. Journal Pharmacological Sciences 101:107-117, 2006

47. Kato G, Yasaka T, Katafuchi T, Furue H, Mizuno M, Iwamoto Y and Yoshimura M. Direct GABAergic and glycinergic inhibition of the substantia gelatinosa from the rostral ventromedial medulla revealed by in vivo patch-clamp analysis in rats. Journal of Neuroscience 26(6):1787-1794, 2006

48. Shiokawa H, Nakatsuka T,Furue H,Tsuda M, Katafuchi T, Inoue K and Yoshimura M. Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors. Journal of Physiology (London) 573(Pt3):753-763, 2006

49. 古江秀昌、玉江昭裕、吉村 恵.In vivo パッチクランプ記録法ー感覚伝達機序のシナプスから分子レベルでの統合的解析ー. Otology Japan 3:223-227, 2006

50. 吉村 恵、古江秀昌.パッチクランプの新手法と今後の展開ーパッチクランプ法ー. Otology Japan 3:219-222, 2006

51. 吉村 恵、古江秀昌. Plasticity and its Implication for Chronic Pain in Spinal Dorsal Horn Neurons. 脊椎脊髄ジャーナル 19(9):912-920, 2006

52. Yoshimura M, Doi A, Mizuno M and Furue H. Methods for in vivo patch-clamp recordings and its applications: synaptic responses in somatosensory cortex. 日本薬理学雑誌 128:381-387, 2006

53. Furue H, Ito A and Yoshimura M. Spinal anti-nociceptive effect of calcitonin in an osteoporotic model rat. - Functional recovery of descending serotonergic inhibition-. CLINICAL CALCIUM 15(3):483-487, 2005

54. 古江秀昌.大脳皮質からのin vivoパッチクランプ法開発. In:ブレインサイエンスレビュー2005(伊藤正男、河合述史編) クバプロ (株)ブレインサイエンス振興財団 pp.37-50, 2005

55. Koga K, Furue H,Rashid MH, Takaki A, Katafuchi T and Yoshimura M. Selective activation of primary afferent fibers evaluated by sine-wave electrical stimulation. Molecular Pain 1(1):13, 2005free article

56. Miyakawa A,Furue H,Katafuchi T, Jiang N, Yasaka T, Kato G and Yoshimura M. Action of neuropeptide Y on nociceptive transmission in substantia gelatinosa of the adult rat spinal dorsal horn. Neuroscience 134(2):595-604, 2005

57. Yoshimura M, Doi A, Mizuno M, Furue H and Katafuchi T. In vivo and in vitro patch-clamp recording analysis of the process of sensory transmission in the spinal cord and sensory cortex. Journal of Physiological Anthropology and Applied Human Science 24(1):93-97, 2005

58. Tamae A, Nakatsuka T, Koga K, Kato G, Furue H, Katafuchi T and Yoshimura M. Direct inhibition of substantia gelatinosa neurones in the spinal cord by activation of dopamine D2-like receptors. Journal of Physiology (London) 568(Pt1):243-253, 2005

59. Matayoshi S, Jiang N, Katafuchi T, Koga K, Furue H, Yasaka T, Nakatsuka T, Zhou XF, Kawasaki Y, Tanaka N and Yoshimura M. Actions of brain-derived neurotrophic factor on the spinal nociceptive transmission during inflammation. Journal of Physiology (London) 569(Pt2):685-695, 2005

60. Shiokawa H, Nakatsuka T,Furue H, Inoue K and Yoshimura M. Functional roles of post-synaptic ATP P2X receptors in spinal deep dorsal hornn neurons. Pain Research 20(1):1-7, 2005

61. Nakatsuka T, Tamae A, Koga K, Kato G, Fujita T, Furue H, Kumamoto E and Yoshimura M.Functional role of postsynaptic dopamine receptors in substantia gelatinosa neurons of the spinal cord. Pain Research 20:105-110, 2005

62. Furue H, Katafuchi T and Yoshimura M. Sensory processing and functional reorganization of sensory transmission under pathologinal conditions in the spinal dorsal horn Neuroscience Research 48 : 361-368, 2004 (Review article)

63. Sonohata M, Furue H, Katafuchi T, Yasaka T, Doi A, Kumamoto E and Yoshimura M. Actions of noradrenaline on substantia gelatinosa neurones in the rat spinal cord revealed by in vivo patch recording. Journal of Physiology 555.2 :515-526, 2004

64. Kato G, Furue H, Katafuchi T, Yasaka T, Iwamoto Y and Yoshimura M. Electrophysiological mapping of the nociceptive inputs to the substantia gelatinosa in rat horizontal spinal cord slices. Journal of Physiology 560.1 : 303-315, 2004

65. Yoshimura M, Furue H, Nakatsuka T and Katafuchi T. Analysis of receptive fields revealed by in vivo patch-clamp recordings from dorsal horn neurons and in situ intracellular recordings from dorsal root ganglion neurons. Life Science 74 : 2611-2618 2004

66. Ito A, Takeda M,Furue H, Shibata K, Hori M, Sagai H, Sakurada T and Yoshimura M. Administration of estrogen shortly after ovariectomuy mimics the anti-nociceptive action and change in 5-HT(1A)-like receptor expression induced by calcitonin in ovariectomized rats. Bone 35(3) : 697-703 2004

67. Moriyama M, Furue H, Katafuchi T, Teranishi H, Sato T, Kano T, Kojima M and Yoshimura M. Presynaptic modulation by neuromedin U of sensory synaptic transmission in rat spinal dorsal horn neurons. Journal of Physiology 559.3 :707-713 2004

68. Tamae A, Nakatsuka T, Sonohata M, Kato G, Furue H and Yoshimura M : The role of dopamine receptors in spinal antinociception. The Journal of Functional Diagnosis of the Spinal Cord 26(1) : 12-16, 2004

69. Kato G, Furue H, Sonohata M, Tamae A, Nakatsuka T, Iwamoto Y and Yoshimura M. The difference between excitatory and inhibitory projection fields of primary nociceptive afferent. The Journal of Functional Diagnosis of the Spinal Cord 26(1) : 17-22, 2004

70. Sonohata M, Furue H, Nakatsuka T, Kato G, Tamae A, Yoshimura M and Hotokebuchi T : In vivo patch-clamp analysis of effects of noradrenaline on spmatosensory input to substantia gelatinosa. The Journal of Functional Diagnosis of the Spinal Cord 26(1) : 29-34, 2004

71. Furue H, Kato G, Kim JH, Min BI, Katafuchi T and Yoshimura M. In vivo patch-clamp analysis of sensory neuronal circuit in the rat superficial spinal dorsal horn. In: Brain- inspired IT I International Congress Series No.1269 (Eds. Nakagawa H, Ishii K and Miyamoto H) Elsevier Science B.V. pp.69-72, 2004

72. Mizuno M, Doi A, Yasaka T, Furue H, Aou S and Yoshimura M. In vivo patch-clamp analysis of synaptic responses in rat primary somatosensory barrel cortex (SI). In: Brain-inspired IT I International Congress Series No.1269 (Eds. Nakagawa H, Ishii K and Miyamoto H) Elsevier Science B.V. pp.73-76, 2004

73. Yoshimura M, Furue H, Nakatsuka T, Matayoshi S and Katafuchi T. Functional reorganization of the spinal pain pathways in developmental and pathological conditions. In:Pathological Pain: From molecular to clinical aspects Novartis Foundation Symposium 261 John Wiley and Sons pp.116-131, 2004

74. 吉村 恵、古江秀昌、加藤 剛、土井 篤、水野雅晴、片渕俊彦 In vivoパッチクランプ記録法の薬理学への応用.日本薬理学雑誌 124:111-118, 2004

75. 吉村 恵、古江秀昌、中塚映政、伊藤彰敏、片渕俊彦. 脊髄可塑性と慢性疼痛.神経研究の進歩 48(6):935-910, 2004

76. Jiang N, Furue H, Katafuchi T and Yoshimura M. Somatostatin directly inhibits substantia gelatinosa neurons in adult rat spinal dorsal horn in vitro. Neuroscience Research 47:97-107, 2003

77. Yang K, Furue H, Fujita T, Kumamoto E and Yoshimura M. Alterations in primary afferent input to substantia gelatinosa of adult rat spinal cord after neonatal capsaicin treatment. Journal of Neuroscince Research 74(6):928-933, 2003

78. Kawasaki Y, Kumamoto E, Furue H and Yoshimura M. Alpha2 adrenoceptor-mediated presynaptic inhibition of primary afferent glutamatergic transmission in rat substantia gelatinosa neurons. Anesthesiology 98(3):682-689, 2003

79. Yang K, Furue H, Kumamoto E, Dong Y-X and Yoshimura M. Pre- and postsynaptic inhibition mediated by GABAB receptors in rat ventrolateral periaqueductal gray neurons. Biochemical and Biophysical Research Communication 302:233-237, 2003

80. Matsumoto N, Kumamoto E, Furue H and Yoshimura M. GABA-mediated inhibition of glutamate release during ischemia in substantia gelatinosa of the adult rat. J. Neurophysiology 89:257-264, 2003

81. Furue H, Sonohata, Ito A, Kawasaki Y, Baba H and Yoshimura M. In vivo patch-clamp analysis of norepinephrine effects on nociceptive transmission in substantia gelatinosa neurons of the rat spinal cord. In: Progress in Pain Research and Management, Proceedings of the 10th World Congress of Pain 24:245-250, 2003

82. 古江秀昌、園畑素樹、吉村 恵.マウスおよびラット脊髄後角細胞からのin vivoパッチクランプ記録法. 日本生理学雑誌 65(10):315-321, 2003

83. 土井 篤、水野雅晴、古江秀昌、吉村 恵:ラット大脳皮質体性感覚野からのin vivo パッチクランプ記録法. 日本生理学雑誌 65(10):322-329, 2003

84. 吉村 恵、古江秀昌.脊髄後角の可塑性と痛み.脳21 金芳堂 6(1):42-47, 2003

85. Nakatsuka T, Furue H, Yoshimura M and Gu J. Activation of central terminal VR1 receptors and alpha-beta-mATP-sensitive P2x receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord. Journal of Neuroscience 2(4): 1228-1237, 2002

86. Luo C, Kumamoto E, Furue H, Chen J, Yoshimura M. Anandamide inhibits excitatory transmission to rat substantia gelationsa neurons in a manner different from that of capsaicin. Neuroscience Letters 321: 17-20, 2002

87. Luo C, Kumamoto E, Furue H, Chen J and Yoshimura M. Nociceptin inhibits excitatory but not inhibitory transmission to substantia gelatinosa neurones of adult rat spinal cord. Neuroscience 109(2):349-58, 2002

88. Lao L-J, Kumamoto E, Fujita T, Luo C, Furue H, Yoshimura M. Cellular mechanisms for the inhibition by adenosine of pain transmission in the spinal dorsal horn. Pain Research 17:63-68, 2002

89. 吉村 恵、古江秀昌、中塚映政、伊藤彰敏.痛みの脊髄機構. 痛みと臨床 2(3):352-355, 2002

90. 吉村 恵、古江秀昌.脊髄痛覚伝達系の可塑性-慢性炎症による痛覚過敏の発生機序-. 医学のあゆみ 203(1):20-24, 2002

91. 吉村 恵、古江秀昌、伊藤彰敏、中塚映政.脊髄スライスおよびin vivoパッチクランプ法を用いた脊髄後角における痛覚伝達系の機能解析.麻酔 51(Suppl):S79-S88, 2002

92. 古江秀昌、中塚映政、伊藤彰敏、吉村 恵.In vivo パッチクランプ法を用いたシナプス応答の解析. In:脳機能の解明 -生命科学の主潮流-(赤池紀扶、東 英穂、阿部康二、久保千春編)ガイア出版会 pp9-15,2002.

93. Yang K, Li YQ, Kumamoto E, Furue H and Yoshimura M. Voltage-clamp recording of postsynaptic currents in substantia gelatinosa neurons in vitro and its applications to assess synaptic transmission. Brain Research Protocols 7:235-240, 2001

94. Lao L-J, Kumamoto E, Luo C, Furue H and Yoshimura M : Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A1 adenosine receptor. Pain 94:315-324, 2001

95. Luo C, Kumamoto E, Furue H and Yoshimura M. Nociceptin-induced outward current in substantia gelatinosa neurones of the adult rat spinal cord. Neuroscience 108(2):323-330, 2001

96. Kawasaki Y, Kumamoto E, Furue H and Yoshimura M. Cellular mechanisms for inhibition by noradrenaline of pain transmission in the spinal dorsal horn. Pain Research 16:69-75, 2001

97. Yoshimura M, Ito A and Furue H. In vivo patch-clamp analysis of plastic changes in serotonergic system on nociceptive transmission at C afferent terminals in ovariectmized rats model. In:Proceedings of International Symposium (Eds. Kim S-S.) Kyung Hee University MedicalCenter 30th Anniversary pp 83-86, 2001

98. 吉村 恵、伊藤彰敏、古江秀昌.骨粗鬆症の痛みの発生とカルシトニンによる静痛作用. CLINICAL CALCIUM 11(9):1153-1157, 2001

99. 吉村 恵、古江秀昌.パッチクランプ法. 新パッチクランプ実験技術法(岡田泰伸編)吉岡書店 pp140-146, 2001

100. 吉村 恵,熊本栄一,古江秀昌,伊藤彰敏.脊髄の痛みとレセプター.ペインクリニック 991-998, 2000

101. 吉村 恵,古江秀昌,成川圭太,熊本栄一.新しいin vivo標本を用いた脊髄痛覚伝達機序の解析. 痛みと漢方 10:8-12, 2000

102. Narikawa K, Furue H, Kumamoto E and Yoshimura M. In vivo whole-cell recording analysis of inhibitory synaptic responses in substantia gelatinosa neurons of the rat spinal cord. Pain Research 15:75-80, 2000

103. Narikawa K, Furue H, Kumamoto E and Yoshimura M. In vivo patch-clamp analysis of IPSCs evoked in rat substantia gelatinosa neurons by cutaneous mechanical stimulation. Journal of Neurophysiology 84:2171-2174, 2000

104. Yang K, Kumamoto E, Furue H, Li Y-Q and Yoshimura M. Capsaicin induces a slow inward current which is not mediated by substance P in substantia gelatinosa neurons of the rat spinal cord.,Neuropharmacology 39:2185-2194, 2000

105. 吉村 恵、古江秀昌、成川圭太、熊本栄一:新しいin vivo 標本を用いた脊髄痛覚伝達機序の解析. 痛みと漢方. 10, 8-12, 2000

106. Furue H, Narikawa K, Kumamoto E and Yoshimura M. Responsiveness of rat substantia gelatinosa neurons to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording. Journal of Physiology(London) 521:529-535, 1999

107. Furue H, Narikawa K, Kumamoto E and Yoshimura M. In vivo whole-cell recording analysis of nociceptive transmission in the rat spinal dorsal horn. Pain Research 14: 73-79, 1999

108. Yang K, Kumamoto E, Furue H, Li Y-Q and Yoshimura M. Action of capsaicin on dorsal root-evoked synaptic transmission to substantia gelatinosa neurons in adult rat spinal cord slices. Brain Research 830: 268-273, 1999

109. Yoshimura M, Furue H, Narikawa K, Kumamoto E and Nakatsuka T. Somatosensory organization in the spinal dorsal horn of adult rats. In:The First Japan-Korea Joint Symposium, (Eds. Akaike N and Ito Y) pp68-76, 1999

110. Yang K, Kumamoto E, Furue H and Yoshimura M. Capsaicin facilitates excitatory but not inhibitory synaptic transmission in substantia gelatinosa of the rat spinal cord. Neuroscience Letters 255:135-138, 1998

111. Furue H and Yoshii K. A method for in-situ tight-seal recordings from single taste bud cells of mice. Journal of Neuroscience Methods 84(1-2):109-114, 1998

112. Furue H and Yoshii K. In-situ tight-seal recordings of taste substance-elicited action currents andvoltage-gated ba currents from single taste bud cells in the peeled epithelium of mouse tongue. Brain Research, 776, 133-139, 1997

113. Furue H, Fudamoto N, Ohtubo Y and Yoshii K. Phenytoin protected mouse cortical cell cultures against neurotoxicity induced by kainate but not by NMDA. Amino Acids 12, 179-184, 1997

114.古江秀昌、吉井清哲. 剥離舌上皮を利用したマウス味蕾細胞測定システム. 日本味と匂学会誌, 2巻 (2号), 55-57, 1995

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シンポジウム・教育講演など(筆頭演者のみ)

1. Furue H. Orofacial stimulation-induced excitation of noradrenergic neurons in the locus coeruleus and its control of nociceptive transmission. 第93回日本生理学会大会(シンポジウム)2016.3.22-24

2. Furue H. Optogenetic control of descending noradrenergic system and in vivo analysis of its antinociceptive action. 第89回日本薬理学会年会(シンポジウム)2016.3.9-11

3. Furue H. Descending pain modulatory system and its activation by systemc slpha 2 agonist. 12th World Congress of Veterinary Anaesthesiology, Kyoto, Japan, 2015.9.1

4. 古江秀昌. Nodulation of sensory synaptic transmission by noradrenergic neurons in the Locus Coeruleus. 第120会日本解剖学会総会・全国学術集会 第92回日本生理学会大会 合同大会 (ランチョンセミナ) 2015.3.21-23

5. Furue H. Modulation of spinal sensory synaptic transmission by TRPV1-expressing afferent fiber. 第120会日本解剖学会総会・全国学術集会 第92回日本生理学会大会 合同大会 (口演) 2015.3.21-23

6. 古江秀昌. 覚醒を司る青斑核と鍼鎮痛の神経機構. 生体制御学会第274回定例講習会 (講演) 2015.3.1

7. Furue H. Mechanism for spinal antinociceptive action of descending noradrenergic neuron in the locus coeruleus. 第36回日本疼痛学会 (招待講演) 2014.6.20-21

8. 古江秀昌. 生理学からみた内因性の鎮痛メカニズム. 第6回信州Opioid研究会 (特別講演) 2014.6.7

9. Furue H. In vivo spinal GABAergic excitation by optogenetic acitvation of descending noradrenergic nuorons in the loucs coeruleus. Korean Pain Consortium Conference, Andong, Korea, 2014.2.20-23

10. Furue H. , Uta D. Pruriceptive synaptic transmission in the spinal cord and descending modulatory system. 第87回日本薬理学会年会 (シンポジウム) 2014.3.19-21

11. 古江秀昌. 生理学からみた鎮痛・発痛メカニズム. 第6回日本運動器疼痛学会(ランチョンセミナ) 2013.12.7-8

12. Furue H and Imoto K. Endogeneous control of pain transmission. 1st CU-NIPS Symposium "Frontier in Physiological Sciences Research: From Basic Research to Diseases and Treatments"(シンポジウム) 2013.10.21-22

13. Furue H, Koga K and Imoto K. In vivo spinal inhibitory synaptic responses evoked by optoactivation of descending noxious inhibitory system. The 11th Japan-Korea joint symposium of Brain Sicences, and Cardiac and Smooth Muscle Scienses(シンポジウム) 2013.9.4-7

14. Furue H. In vivo analysis of spinal GABAergic inhibition of nociceptive transmission. 第90回日本生理学会大会(シンポジウム) 2012.3.27-29

15. 古江秀昌. 活動電位と痛覚伝達. 第90回日本生理学会大会 生理学モデル講義 2013.3.28

16. Furue H. In vivo patch clamp analysis of spinal modulation of nociceptic synaptic transmission by optoactivation of the locus soeruleus. NIPS International Workshop - Central Neuroplasticity in Sensory-Emotional LInk(シンポジウム) 2012.9.13-15

17. 古江秀昌. 神経生理学からみた内因性痛覚抑制機序とその減弱による疼痛発現機序. 日本麻酔科学会第59回学術集会(招待講演) 2012.6.9

18. Furue H. In vivo patch-clamp analysis of pontspinal descending inhibitory control of pain. 第89回日本生理学会大会(シンポジウム) 2012.3. 30

19. Furue H. Stimulation of the locus coeruleus modulates synaptic transmission in the rat superficial dorsal horn in vivo. 第88回日本生理学会大会 2011.3(誌上発表)

20. Furue H. In vivo patch-clamp analysis of surround inhibition of nociceptive transmission in the superficial spinal dorsal horn. Korean Pain Research Consortium (KRPC) Symposium, Seoul, Korea, 2010.6.11

21.Furue H. Impaired noxious cold synaptic transmission in the spinal cord of mice lacking a cell-cell adhesion molecule, cadherin. Seminar at Seoul National University School of Dentistry, Seoul, Korea, 2010.6.10

22. 古江秀昌.In vivo 痛覚シナプス伝達の解析.第5回名古屋大学環境医学研究所・生理学研究所 合同シンポジウム 2010.1.29

23. Furue H. Impaired cold synaptic transmission in the spinal dorsal horn of mice lacking a cell-cell adhesion molecule. Special Seminar, at University of Maryland - Baltimore, Baltimore, USA 2009.10.22 PDFファイル

24. 古江秀昌.細胞接着因子と痛みのシナプス伝達.日本ペインクリニック学会大43回大会・第31回日本疼痛学会(シンポジウム)2009.7.17

25. 古江秀昌.GABAを介した痛覚伝達抑制機序.丸石製薬株式会社(講演)2009.4.24

26. 古江秀昌.In vivoパッチクランプ法を用いた痛覚伝達回路の解析.生理学研究所研究会 大脳皮質機能単位の神経機構 2008.11.27

27. 古江秀昌.生理学の立場から工学異性体の末梢神経(DRG)への作用の違い.日本臨床麻酔学会第28回大会(シンポジウム)2008.11.22

28. 古江秀昌.脊髄後角におけるモダリティ依存的なシナプス入力とその抑制回路.生理学研究所部門公開セミナー 2008.9.25

29. Furue H. In vivo patch-clamp analysis of plastic changes in spinal sensory transmission. Seminars in Physiology and Pharmacology, at University of Bristol, Bristol, UK 2008.8.13

30. 古江秀昌.痛覚情報伝達とその異常における抑制性シナプス伝達の意義.東京慈恵会医科大学、医学研究の基礎を語り合う集い(講演)2008.2.25

31. Furue H and Yoshimura M. Functional loss of synaptic inputs to spinal superficial dorsal horn neurons through cold-sensitive afferent fibers in cadherin-8 deficient mice. The 7th Japan-Korea Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscles, 2007.12.7-9 Symposium

32. 古江秀昌. GABAを介した痛みの周辺抑制と痛覚伝達系の異常. 関西医科大学大学院講座第575講 2007.12.4

33. Furue H, Kato G, Yasaka T and Yoshimura M. Surround inhibition of nociceptive transmission in the superficial spinal dorsal horn through activation of tactile C afferent fiber. -In vivo patch-clamp analysis of modality dependent synaptic responses-. The 83rd Annual Meeting of the Physiological Society of Japan, 2006.3.28-30 Symposium.

34. 古江秀昌.痛覚伝達系とその異常の電気生理学的研究法―In vivoパッチクランプ法を用いた解析―. 日本ペインクリニック学会第40回大会・第28回日本疼痛学会合同大会, 2006.7.13-15 

35. 古江秀昌.電気生理とパッチクランプ法. 第8回ブレインサイエンス研究会, 2006.6.10-11 (テクニカルセミナー)

36. 古江秀昌.パッチクランプの新手法と今後の展開について 2.In vivo patch.第24回聴覚生理研究会, 2005.10.22 

37. 古江秀昌、又吉 達、中塚映政、吉村 恵.末梢炎症に伴う慢性疼痛発現機序の解析-脊髄痛覚回路の可塑性と神経栄養因子-.第24回鎮痛薬・オピオイドペプチドシンポジウム, 2003.9

38. Furue H, Kawasaki Y, Baba H, Kumamoto E and Yoshimura M. Pre- and post-synaptic actions of noradrenaline on nociceptive transmission in substantia gelatinosa neurons of the rat spinal cord. The Third Japan-Korea Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscles, 2002.1

39. Furue H, Matayoshi S, Nakatsuka T and Yoshimura M. In vivo patch-clamp analysis of plastic changes in nociceptive transmission in the spinal dorsal horn after peripheral inflammation. 第3回ニューロサイエンスワークショップ in 九州, 2002.11.

40. Furue H, Narikawa K, Kumamoto E, Ito A and Yoshimura M. In vivo patch-clamp analysis of excitatory and inhibitory synaptic responses evoked by noxious and innoxious stimuli in rat spinal dorsal horn neurons. 第2回九州脳シンポジウム, 2002.1.

41. 古江秀昌.In vivo パッチクランプ法を用いた慢性疼痛発現機序の解析.第2回群馬ペインクリニック懇話会 群馬 2001.11.17

42. 古江秀昌、伊藤彰敏、吉村 恵.In vivo パッチクランプ法を用いた脊髄痛覚伝達機序の解析.第4回ブレインサイエンス研究会, 2001.7
古江秀昌、吉村 恵,:In vivo パッチクランプ法による脊髄痛覚伝達機序の解明.日本ペインクリニック学会第33回大会, 1999.7

 

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