Department of Gastroenterology Division of Hepatobiliary and Pancreatic Diseases

Our department focuses on clinical research into the diagnosis and treatment of gastrointestinal diseases, particularly liver, biliary and pancreatic diseases, with the aim of establishing new biomarkers and improving treatment outcomes. We also conduct research into chronic liver disease from a nutritional perspective, non-invasive diagnostic methods using ultrasound examinations, research into improving outcomes of liver cancer treatment, and research into early diagnosis and optimal treatment of malignant biliary and pancreatic diseases using ultrasound endoscopy and molecular biology analysis.

We are conducting basic research into the early diagnosis of NASH, which is an increasingly common liver disorder associated with metabolic syndrome, obesity, and diabetes.

We are conducting clinical research into the treatment of refractory viral hepatitis, research into carcinogenesis after viral elimination, as well as elucidating the pathology of portal hypertension and autoimmune liver disease, etc. We aim to improve prognosis by combining drug therapy with lifestyle modification.

Regarding chemotherapy for advanced liver cancer using immune checkpoint therapy and molecular targeted drugs, we are examining treatment options and early treatment efficacy assessment factors, and developing localized treatment methods using the latest ultrasound technology.

We aim to improve the prognosis of pancreatic cancer, an intractable cancer, by conducting genetic and proteomic analyses using blood, cells, and tissues provided by patients with pancreatic cancer and precancerous lesions.

Using endoscopic ultrasound, we are developing new treatment algorithms that combine minute blood flow dynamics and treatment sensitivity in pancreatic cancer.

We aim to establish a minimally invasive treatment method by comparatively examining conventional drainage methods and a new drainage method using ultrasound endoscopes.

In order to improve the prognosis of severe infectious encapsulated necrosis, we are working to develop optimal treatment strategies. Through these research activities, we will select the latest diagnostic and treatment methods in collaboration with surgical and radiology specialists in consultation with patients.