業績

Publications

2023

総説

多田教浩, 江嵜啓祥, 伊藤彰近, アルキニル超原子価ヨウ素化合物を用いる求電子的アルキニル化およびアルケニル化反応, 有機合成化学協会誌, 2023, 81, 1178-1189.

2022

原著論文

Shimizu, A.; Shibata, A.; Kano, T.; Kumai, Y.; Kawakami, R.; Esaki, H.*;Fukushima, K.; Tada, N.; Itoh, A. Synthesis of 4-Imidazolidinones from Diamides and Ethynyl Benziodoxolones via Double Michael-Type Addition: Ethynyl Benziodoxolones as Electrophilic Ynol Synthons, Org. Lett. 2022, 24, 8859–8863. DOI: org/10.1021/acs.orglett.2c03648

その他

Shimizu, A.; Shibata, A.; Esaki, H.; Fukushima, K.; Tada, N.; Itoh, A.; Synthesis of 4-Imidazolidinones from Diamides and Ethynyl Benziodoxolones via Double Michael-Type Addition: Ethynyl Benziodoxolones as Electrophilic Ynol Synthons, ChemRxiv, chemrxiv-2022-bb2bt, 2022

2021

原著論文

1. Fukushima, K.; Esaki, H. Theoretical Study of the Mechanism of Ribosomal Peptide Bond Formation Using the ONIOM Method, Chem. Pharm. Bull. 2021, 69, 734−740.

2. Toda, Y.; Yoshida, T.; Arisue, K.; Fukushima, K.; Esaki, H.; Kikuchi, A.; Suga, H. Enantioselective Protonation of Cyclic Carbonyl Ylides by Chiral Lewis Acid Assisted Alcohols, Chem. Eur. J., 27, 10578−10582, 2021

 

2019

原著論文

1. Toda, Y.; Komiyama, Y.; Esaki, H.; Fukushima, K.; Suga,H. Methoxy Groups Increase Reactivity of Bifunctional Tetraarylphosphonium Salt Catalysts for Carbon Dioxide Fixiation: A Mechanistic Study. J. Org. Chem. 2019, 84, 15578-15589. DOI: 10.1021/acs.joc.9b02581

2018

原著論文

1. Toda, Y.; Koyama, M.; Esaki, H.; Fukushima, K.; Suga,H. Enantioselective Cycloadditions between Aliphatic Nitrile Oxides and 2-Hydroxystyrenes Catalyzed by Chiral Amine-Urea. HETEROCYCLES 2018, 97, 147-150. DOI: 10.3987/COM-17-S(T)7

2017

原著論文

1. 福島和明;量子化学計算を用いたペプチド結合形成のメカニズムの解明.兵庫医科大学医学会雑誌, 42, 39-44.

2. H. Suga, Y. Hashimoto, Y. Toda, K. Fukushima, H. Esaki, A. Kikuchi; Amine-Urea-Mediated Asymmetric Cycloadditions between NitrileOxides and o-Hydroxystyrenes by Dual Activation. Angew. Chem. Int. Ed. 2017, 56, 11936-11939. DOI: 10.1002/anie.201705662

著書

1. Hiroyoshi Esaki (2017). Pd on Spherical Carbon (Pd/SC)-Catalyzed Chemoselective Hydrogenation. In Kiyoshi Tomioka, Takayuki Shioiri, Hironao Sajiki (Eds.), New Horizons of Process Chemistry-Scalable Reactions and Technologies-:Springer Nature, Singapore (41-50). ISBN: 978-981-10-3420-6

その他

1. 江嵜 啓祥; プロトン共役電子移動を利用する遠隔位C(sp3)-H結合の直接官能基化.ファルマシア,2017,53 (5),466.

2015

総説

1. 野坂和人, 江嵜啓祥;ヒト大腸上皮細胞膜に存在するチアミンピロリン酸トランスポーター.ビタミン,2015,89 (9),459-461.

2014

原著論文

1. Hatae N, Nagayama T, Esaki H, Kujime E, Minami M, Ishikura M, Choshi T, Hibino S, Okada C, Toyota E, Nagasawa H, Iwamura T:Synthesis of 4-arylpiperidin-4-ol derivatives of loperamide as agents with potent antiproliferative effects against HCT-116 and HL-60 Cells. Heterocycles2014, 88(1), 663-673. DOI: 10.3987/COM-13-S(S)20

2. Hayashi M, Kobayashi K, Esaki H, Konno H, Akaji K, Tazuya K, Yamada K, Nakabayashi T, Nosaka K: archaeal thiamin phosphate synthase. Biochim. Biophys. Acta. 2014, 1844(4), 803-809.
DOI: 10.1016/j.bbapap.2014.02.017

その他

1. 石井拓,武田好史,竹山重光,田中晴喜,平井秀一,福島和明,藤村寿子,本郷正武,牧野誠司,山崎尚:2014年「夏の公開講座」の記録、和歌山県立医科大学医学部教養・医学教育大講座紀要,2014,44,35-54.

2013

原著論文

1. Esaki H, Hattori T, Tsubone A, Mibayashi S, Sakata T, Sawama Y, Monguchi Y, Yasuda H, Nosaka K, Sajiki H:Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon. Chem Cat Chem, 5(12), 3629-3635, 2013.
DOI: 10.1002/cctc.201300639

総説

1. 野坂和人,江嵜啓祥:トランスケトラーゼ様タンパク質はトランスケトラーゼ活性を持たない. ビタミン,2013,87 (11),629-631.

その他

1. 錦見盛光,福島和明,古市幸生:「酸性食品」・「アルカリ性食品」の栄養学的意義についての再考. 名古屋女子大学紀要,2013,59,家政・自然編29-39.

2. 武田好史,竹山重光,田中晴喜,平井秀一,福島和明,藤村寿子,本郷正武,牧野誠司,山崎尚:公開講座の紹介と記録,和歌山県立医科大学医学部教養・医学教育大講座紀要,2013,43,19-55.

2012

原著論文

1. Nosaka K, Esaki H, Onozuka M, Konno H, Hattori Y, Akaji K: Facilitated recruitment of Pdc2p, a yeast transcriptional activator, in response to thiamin starvation. FEMS Microbiol. Lett. 2012,330(2), 140-147.
DOI: 10.1111/j.1574-6968.2012.02543.x

2. Fukushima K, Iwahashi H, Nishikimi M:ONIOM Study of a Proton Shuttle-Catalyzed Stepwise Mechanism for Peptide Bond Formation in the Ribosome. Bull. Chem. Soc. Jpn., 85 (10), 1093-1101, 2012.
DOI: 10.1246/bcsj.20120144

総説

野坂和人,江嵜啓祥:リボスイッチを標的とする抗菌剤の開発. ビタミン,2012,86 (11),647-649.

その他

Fukushima K: Quantum Chemical Calculations of Specific Pairs of Nucleosides using Gaussian 09 Program. Bulletin of Wakayama Medical University (Liberal Arts and Sciences), 42, 21-36, 2012.

2011

原著論文

Minakata K, Fukushima K, Nakamura M, Iwahashi H: Effect of some naturally occurring iron chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe3+ and NADPH. J. Clin. Biochem. Nutr. 2011, 49(3), 207-215.
DOI:org/10.3164/jcbn.11-16

総説

野坂和人,江嵜啓祥,小野塚真理,今野博行,服部恭尚,赤路健一:酵母の転写因子Pdc2によるチアミン依存性転写誘導機構.ビタミン,2011,85(10), 538-546.

その他

Fukushima K, Quantum Chemical Calculations on Hydrogen Bonding Dimer of Formic Acid Using Gaussian-n Theories, Bulletin of Wakayama Medical University (Liberal Arts and Sciences), 2011,41, 1-19.

2010

その他

Fukushima K, ONIOM Study of Neutral and Zwitterionic Intermediates in Stepwise Mechanism for Peptide Bond Formation in the Ribosome, Bulletin of Wakayama Medical University (Liberal Arts and Sciences), 2010,40, 1-11.