Pharmaceutics and Pharmaceutical Technology

We are investigating the mechanisms by which cancer cells acquire resistance to anticancer drugs and exploring strategies to overcome this resistance from both pharmaceutics and clinical pharmacy perspectives.

In cancer chemotherapy, one of the major clinical challenges is the emergence of drug resistance in cancer cells. To address this, we have developed novel drug-resistant cancer cell lines across a range of anticancer agents, including molecularly targeted therapies, and are analyzing the underlying mechanisms of this resistance. Using these resistant cell lines, we are also exploring methods to potentially reverse drug resistance. Additionally, we are examining factors influencing the efficacy of anticancer drugs in cancer cells derived from various tumor types, with the goal of identifying safer and more effective approaches to cancer treatment.