Introduction to each specialty (Graduate School of Pharmacy)

Aiming for individualized and appropriate drug administration, we provide research guidance on the following themes based on Pharmacogenomics/Pharmacoepigenomics and molecular pharmacokinetics. The main theme of the research theme is "Establishment of personalized medicine," and the main research will make full use of Department of Pharmacology, molecular Department of Pharmacology, molecular pharmacokinetics, and mathematical analysis.

In order to develop next-generation testing and treatment methods, we design and synthesize new materials such as fluorescent probe molecules for visualizing substances in the body, protein labeling reagents, and luminescent, photocatalytic, and magnetic nanomaterials, and clarify their structures and physical properties. To this end, we are working on the following research themes using Physical Chemistry and analytical chemical techniques and methodologies.

With a view to expanding the role of pharmacists in medical care, we will clarify various issues, particularly those related to drug administration, and conduct research aimed at developing the systems and devices necessary to resolve these issues and individual optimization of drug therapy. We will also conduct research related to self-medication and self-care. Specifically, we will work on the following research themes and promote research aimed at improving the social status of pharmacists.

We aim to overcome cancer and chronic inflammation through research into the healthy use of reactive oxygen species and immune control.
Using Department of Biochemistry, Molecular Biology biology, and Department of Immunology techniques, we will tackle the following themes:

We use Molecular Biology biological, Physiology, and behavioral Department of Pharmacology techniques to analyze neurological conditions such as chronic intractable pain and ischemic neuropathy, and to elucidate their onset mechanisms. We also develop drug-based methods to control these conditions and explore the seeds of their clinical application.

We conduct next-generation medicinal chemistry research with the aim of developing new pharmaceuticals and building the fundamental new technologies that support them. We provide research guidance to advance not only Organic Chemistry chemistry, but also medicinal chemistry and Medicinal Chemistry (Chemical Biology), making full use of organic chemistry and computational chemistry techniques. We also search for compounds that can become pharmaceutical seeds from natural resources such as marine organisms and medicinal plants using screening evaluation systems developed based on the latest knowledge. We aim to develop the discovered physiologically active compounds as pharmaceutical seeds by analyzing their action and optimizing them through chemical induction, with the aim of developing lead compounds for clinical use. We will tackle the research themes listed below and develop advanced research skills.

We conduct chemistry-based research into clinical medicines. We are able to conduct wet research centered on experiments, and dry research centered on data analysis.
In wet research, we will conduct drug repositioning, which develops existing drugs or their metabolites into new pharmaceuticals, and exploratory synthesis research using existing drugs as seed compounds. Furthermore, from 2022, we will also conduct research on the development of organic reactions.
In the Dry Research, we are conducting research into adverse drug events databases using JADER and FAERS. Furthermore, we would like to develop clinical research based on the information obtained from the database analysis. We are also conducting pharmaceutical education research aimed at improving the quality of pharmacists.

We are conducting research using Microbiology, biochemical, Department of Biochemistry, Department of Pharmacology and Molecular Biology techniques to control pathogenic microorganisms that cause blood-borne infections and emerging and re-Department of Immunology infectious diseases, as well as harmful microorganisms that cause microbial contamination and deterioration. The main research themes are as follows:

In modern society, due to an aging society and environmental factors such as smoking, air pollution, and asbestos exposure, a wide range of respiratory diseases are steadily increasing, including malignant respiratory tumors such as lung cancer and malignant mesothelioma, chronic obstructive pulmonary disease (COPD), bronchial asthma, an allergic disease, interstitial pneumonia and pulmonary fibrosis, which are intractable respiratory diseases, and pneumonia and pulmonary tuberculosis, which are respiratory infections. However, the pathology and treatment methods for these diseases have not been fully elucidated or established, and they are still an unknown field.
In this research guidance subject field, we will develop research capabilities by conducting basic and clinical research using cells and animals such as mice, aiming at (1) establishing biomarkers that can be used clinically, (2) elucidating pathological mechanisms, and (3) developing new treatment methods. We will also provide guidance so that you can present the results of your research at academic conferences and in papers and obtain a degree.