Publications

2025年

Ohshima K.
The Landscape of Cancer Metabolism as a Therapeutic Target
Pathology International 2025; 75(8): 387-402. Pubmed 
 

2024年

Noma T, Makino T, Ohshima K, Yamashita K, Saito T, Tanaka K, Yamamoto K, Takahashi T, Kurokawa Y, Nakajima K, Morii E, Eguchi H, Doki Y.
CD45RO-Positive Memory T-Cell Density in the Tumoral Core and Invasive Margin Predict Long-Term Survival in Esophageal Squamous Cell Carcinoma
Annals of Surgical Oncology 2025; 32(3): 1953-1962. Epub 2024 Dec Pubmed
 

2023年

Fujino S, Miyoshi N, Kitakaze M, Yasui M, Ohue M, Osawa H, Ide Y, Sueda T, Tei M, Takeda T, Danno K, Suzuki Y, Noura S, Ohshima K, Morii E, Takahashi H, Uemura M, Yamamoto H, Murata K, Doki Y, Eguchi H; Clinical Study Group of Osaka University, Colorectal Cancer Treatment Group (CSGOCG).
Lymph node metastasis in T1 colorectal cancer: Risk factors and prediction model
Oncology Letters 2023; 25(5): 191. Pubmed
Hayashi Y, Makino T, Sato E, Ohshima K, Nogi Y, Kanemura T, Honma K, Yamashita K, Saito T, Tanaka K, Yamamoto K, Takahashi T, Kurokawa Y, Miyata H, Nakajima K, Wada H, Morii E, Eguchi H, Doki Y.
Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint inhibitors
British Journal of Cancer 2023; 128(12): 2175-2185. Pubmed
Kido K, Nojima S, Motooka D, Nomura Y, Kohara M, Sato K, Ohshima K, Tahara S, Kurashige M, Umeda D, Takashima T, Kiyokawa H, Ukon K, Matsui T, Okuzaki D, Morii E.
Ovarian high-grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance
The Journal of Pathology 2023; 260(1): 56-70. Pubmed
 

2022年

Onishi T, Takashima T, Kurashige M, Ohshima K, Morii E.
Mutually exclusive expression of EZH2 and H3K27me3 in non-small cell lung carcinoma
Pathology - Research and Practice 2022; 238: 154071. Pubmed
Tsuchihashi K, Miyoshi N, Fujino S, Kitakaze M, Ohue M, Danno K, Nakamichi I, Ohshima K, Morii E, Uemura M, Doki Y, Eguchi H.
Risk Factors for Predicting Lymph Node Metastasis in Submucosal Colorectal Cancer
Journal of the Anus, Rectum and Colon 2022; 6(3): 181-189. Pubmed
Nojima S, Ishida S, Terayama K, Matsumoto K, Matsui T, Tahara S, Ohshima K, Kiyokawa H, Kido K, Ukon K, Yoshida SY, Mitani TT, Doki Y, Mizushima T, Okuno Y, Susaki EA, Ueda HR, Morii E.
A Novel Three-Dimensional Imaging System Based on Polysaccharide Staining for Accurate Histopathological Diagnosis of Inflammatory Bowel Diseases
Cellular and Molecular Gastroenterology and Hepatology 2022; 14(4): 905-924. Pubmed
Kiyokawa H, Abe M, Matsui T, Kurashige M, Ohshima K, Tahara S, Nojima S, Ogino T, Sekido Y, Mizushima T, Morii E.
Deep Learning Analysis of Histologic Images from Intestinal Specimen Reveals Adipocyte Shrinkage and Mast Cell Infiltration to Predict Postoperative Crohn Disease
American Journal of Pathology 2022; 192(6): 904-916. Pubmed
Ohshima K, Oi R, Nojima S, Morii E.
Mitochondria govern histone acetylation in colorectal cancer
The Journal of Pathology 2022; 256(2): 164-173. Pubmed
 

2021年

Ohshima K, Oi R, Okuzaki D, Motooka D, Shinohara M, Nojima S, Morii E.
Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling
British Journal of Cancer 2021; 125(12): 1699-1711. Pubmed
Tahara S, Nojima S, Ohshima K, Hori Y, Sato K, Kurashige M, Matsui T, Okuzaki D, Morii E.
Nicotinamide N-methyltransferase is related to MELF pattern invasion in endometrioid carcinoma
Cancer Medicine 2021; 10(23): 8630-8640. Pubmed
Noma T, Makino T, Ohshima K, Sugimura K, Miyata H, Honma K, Yamashita K, Saito T, Tanaka K, Yamamoto K, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Morii E, Eguchi H, Doki Y.
Immunoscore Signatures in Surgical Specimens and Tumor-Infiltrating Lymphocytes in Pretreatment Biopsy Predict Treatment Efficacy and Survival in Esophageal Cancer
Annals of Surgery 2023; 277(3): e528-e537. Epub 2021 Jul. Pubmed
Kusumoto S, Kurashige M, Ohshima K, Tahara S, Matsui T, Nojima S, Hattori S, Morii E.
An immature inhibin-α-expressing subpopulation of ovarian clear cell carcinoma cells is related to an unfavorable prognosis
Cancer Medicine 2021; 10(5): 1485-1500. Pubmed
Ohshima K, Morii E.
Metabolic Reprogramming of Cancer Cells during Tumor Progression and Metastasis
Metabolites 2021; 11(1): 28. Pubmed
Yamada T, Ohshima K, Noma T, Yamasaki M, Doki Y, Morii E.
A case of submucosal tumor-like gastric carcinoma diagnosed after a long-term course
診断病理 2021; 38(4): 383-387
 

2020年

Ohshima K, Nojima S, Tahara S, Kurashige M, Kawasaki K, Hori Y, Taniguchi M, Umakoshi Y, Okuzaki D, Wada N, Ikeda JI, Fukusaki E, Morii E.
Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine
Nature Metabolism 2020; 2(1): 81-96. Pubmed
Ogata M, Ohshima K, Ichihara M, Takahashi H, Morii E.
PAX 8-positive sarcomatoid carcinoma arising from the liver with aggressive phenotype: An autopsy case
Pathology International  2020; 70(10): 825-827. Pubmed
Kawasaki K, Nojima S, Hijiki S, Tahara S, Ohshima K, Matsui T, Hori Y, Kurashige M, Umeda D, Kiyokawa H, Kido K, Okuzaki D, Morii E.
FAM111B enhances proliferation of KRAS-driven lung adenocarcinoma by degrading p16
Cancer Science 2020; 111(7): 2635-2646. Pubmed
 

2019年

Tahara S, Nojima S, Ohshima K, Hori Y, Kurashige M, Wada N, Motoyama Y, Okuzaki D, Ikeda JI, Morii E.
Serum deprivation-response protein regulates aldehyde dehydrogenase 1 through integrin-linked kinase signaling in endometrioid carcinoma cells
Cancer Science 2019; 110(5): 1804-1813. Pubmed
 

2018年

Kurashige M, Kohara M, Ohshima K, Tahara S, Hori Y, Nojima S, Wada N, Ikeda JI, Miyamura K, Ito M, Morii E.
Origin of cancer-associated fibroblasts and tumor-associated macrophages in humans after sex-mismatched bone marrow transplantation
Communications Biology 2018; 1: 131. Pubmed
Wada N, Nojima S, Tahara SI, Ohshima K, Kurashige M, Kawasaki K, Tone M, Kusumoto S, Ikeda JI, Morii E.
Effect of glutamine on lymphoplasmacytic lymphoma, especially on the viewpoint of the differentiation into vulnerable subpopulation
Pathology - Research and Practice 2018; 214(10): 1667-1674. Pubmed
Park H*, Ohshima K*, Nojima S, Tahara S, Kurashige M, Hori Y, Okuzaki D, Wada N, Ikeda JI, Morii E. (* equally contribution)
Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate
Laboratory Investigation 2018; 98(4): 449-461. Pubmed
 

2017年

Nojima S, Susaki EA, Yoshida K, Takemoto H, Tsujimura N, Iijima S, Takachi K, Nakahara Y, Tahara S, Ohshima K, Kurashige M, Hori Y, Wada N, Ikeda JI, Kumanogoh A, Morii E, Ueda HR.
CUBIC pathology: three-dimensional imaging for pathological diagnosis
Scientific Reports 2017; 7(1): 9269. Pubmed
Ohshima K, Tsujii Y, Sakai K, Oku H, Morii E.
Massive tumor embolism in the abdominal aorta from pulmonary squamous cell carcinoma: Case report and review of the literature
Pathology International 2017; 67(9): 467-471. Pubmed
Takasugi J, Sakaguchi M, Oyama N, Gon Y, Terasaki Y, Sasaki T, Nakahara S, Ohshima K, Hori Y, Morii E, Mochizuki H.
Recurrent Stroke Due to Metastatic Pulmonary Tumor Emboli as an Important Clinical Entity
Journal of Stroke and Cerebrovascular Diseases 2017; 26(6): e108-e110. Pubmed
Ohshima K, Nojima S, Tahara S, Kurashige M, Hori Y, Hagiwara K, Okuzaki D, Oki S, Wada N, Ikeda JI, Kanai Y, Morii E.
Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer
Scientific Reports 2017; 7: 45504. Pubmed
 

2016年

Yamashita Y, Kusakabe S, Toda J, Ohshima K, Masaie H, Yagi T, Yoshida H, Ishikawa J.
Sequential Onset of Varicella-Zoster Virus Encephalomeningitis and Progressive Multifocal Leukoencephalopathy in an Allogeneic Hematopoietic Stem Cell Transplant Recipient
Experimental and Clinical Transplantation 2018; 16(5): 628-630. Epub 2016 Pubmed
Ikeda JI, Kohara M, Tsuruta Y, Nojima S, Tahara S, Ohshima K, Kurashige M, Wada N, Morii E.
Immunohistochemical analysis of the novel marginal zone B-cell marker IRTA1 in malignant lymphoma
Human Pathology 2017; 59: 70-79. Epub 2016 Pubmed
Tahara S, Nojima S, Ohshima K, Hori Y, Kurashige M, Wada N, Ikeda J, Morii E.
S100A4 accelerates the proliferation and invasion of endometrioid carcinoma and is associated with the "MELF" pattern
Cancer Science 2016; 107(9): 1345-52. Pubmed
Wada N, Ikeda J, Nojima S, Tahara S, Ohshima K, Okuzaki D, Morii E.
Requirement of CXCL12-CXCR7 signaling for CD20(-) CD138(-) double-negative population in lymphoplasmacytic lymphoma
Laboratory Investigation 2016; 96(5): 517-25. Pubmed
 

2015年

Ohshima K, Umeda A, Hosoi A, Yamamoto T, Munakata S.
Mature Cystic Teratoma in Douglas' Pouch
Case Reports in Pathology 2015; 202853. Pubmed
 

2013年

Yoshida H, Ohshima K, Toda J, Kusakabe S, Masaie H, Yagi T, Ishikawa J.
Significant improvement following combination treatment with mefloquine and mirtazapine in a patient with progressive multifocal leukoencephalopathy after allogeneic peripheral blood stem cell transplantation
International Journal of Hematology 2014; 99(1): 95-9. Epub 2013 Pubmed
 

2009年

Moriwaki K, Noda K, Furukawa Y, Ohshima K, Uchiyama A, Nakagawa T, Taniguchi N, Daigo Y, Nakamura Y, Hayashi N, Miyoshi E.
Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling
Gastroenterology 2009; 137(1): 188-98, 198.e1-2. Pubmed
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